Hmmm - I have no idea why these particular monsters should be causing you so much grief.
What I would try in a case like this is to take a trip back to town and see if that doesn't "neutralize" their bad effect. They should not be able to follow you all the way back to town and if you are able to enter there without the game freezing, I think your chances of the castle finally being open to you will be improved.
If that too fails - restore your game to an earlier save.
Wyv
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