Here's a stupid/fun thing to do if you want to ruin any chances you've got of finishing the game:
When you enter the Rapax Away Camp carrying your artifacts, store them in a chest there while you wander around.
And make sure you save your game AFTER you do that.
Which meants that when you have to reload because of a mistake you made, the game reloads to JUST THE EMPTY WILDERNESS CLEARING.
Thereby taking your artifacts into oblivion along with the rest of the away camp and rendering all of your efforts until that moment futile unless you happen to have a save from prior to entering the away camp.
(Told you it was stupid, but guess who managed to do it anyway?

Good thing I've got plenty of older saves!

)